TY - JOUR 
T1 - Leucas aspera to Treat Pan Oral Disorders - An Experimental Study.
A1 - Nagarajan S. Karthika
A1 - Rani Vidya 
A1 - Narayanasamy Aravindhababu 
A1 - Masthan Mahaboob Kadar
Y1 - 2019-07-23
N2 - This article aimed at discussing the effectiveness of developing a new antioxidant and anti-inflammatory product from the natural source namely the extract of Leucas aspera plant that can be used to treat various oral mucosal conditions. The study was a descriptive experimental study. The dried powder extract of the whole LA plant was subjected to various procedures such as phytochemical analysis, antioxidant assay (DPPH) and assessment of anti-inflammatory effect (Cytokine activity in RAW 264.7 macrophage cells) and the results were tabulated. Significance of anti-inflammatory activity was tested by T-test. Our analysis has confirmed that 100µg of plant extract showed high amount of antioxidant activity (78%). The cytokine inhibitory percentage of our plant extract showed consistent increase when tested from 250 ug/ml to 1000ug/ml to be from 24% to 39% thus demonstrating significantly high level of anti-inflammatory potential (P > 0.01). Our study suggests that LA plant can be safely utilized for testing and developing products based on its extract.
JF - Current Dental Research Journal
JA - 
VL - 8
IS - 9
UR - dentaljournal.org/article/4/
SP - 
EP - 
PB - 
M3 - 10.12944/EDJ.01.01.05
ER -