AU - Nagarajan S. Karthika
T1 - Leucas aspera to Treat Pan Oral Disorders - An Experimental Study.
PT - Article
AU - Rani Vidya 
T1 - Leucas aspera to Treat Pan Oral Disorders - An Experimental Study.
PT - Article
AU - Narayanasamy Aravindhababu 
T1 - Leucas aspera to Treat Pan Oral Disorders - An Experimental Study.
PT - Article
AU - Masthan Mahaboob Kadar
T1 - Leucas aspera to Treat Pan Oral Disorders - An Experimental Study.
PT - Article
DP - 2019 Jul 23,
TA - Current Dental Research Journal
PG - 26-33
VI - 8
IP - 9
4099 - dentaljournal.org/article/4/
4100 - dentaljournal.org/article/4/
AB - This article aimed at discussing the effectiveness of developing a new antioxidant and anti-inflammatory product from the natural source namely the extract of Leucas aspera plant that can be used to treat various oral mucosal conditions. The study was a descriptive experimental study. The dried powder extract of the whole LA plant was subjected to various procedures such as phytochemical analysis, antioxidant assay (DPPH) and assessment of anti-inflammatory effect (Cytokine activity in RAW 264.7 macrophage cells) and the results were tabulated. Significance of anti-inflammatory activity was tested by T-test. Our analysis has confirmed that 100µg of plant extract showed high amount of antioxidant activity (78%). The cytokine inhibitory percentage of our plant extract showed consistent increase when tested from 250 ug/ml to 1000ug/ml to be from 24% to 39% thus demonstrating significantly high level of anti-inflammatory potential (P > 0.01). Our study suggests that LA plant can be safely utilized for testing and developing products based on its extract.