%A  Nagarajan S. Karthika
%A  Rani Vidya 
%A  Narayanasamy Aravindhababu 
%A  Masthan Mahaboob Kadar
%T  Leucas aspera to Treat Pan Oral Disorders - An Experimental Study.
%9  Article
%D  
%J  Current Dental Research Journal
%R  10.12944/EDJ.01.01.05
%P  26-33
%V  8
%N  9
%U  dentaljournal.org/article/4/
%8 - July 23,2019
%x - <b>Abstract:</b>This article aimed at discussing the effectiveness of developing a new antioxidant and anti-inflammatory product from the natural source namely the extract of Leucas aspera plant that can be used to treat various oral mucosal conditions. The study was a descriptive experimental study. The dried powder extract of the whole LA plant was subjected to various procedures such as phytochemical analysis, antioxidant assay (DPPH) and assessment of anti-inflammatory effect (Cytokine activity in RAW 264.7 macrophage cells) and the results were tabulated. Significance of anti-inflammatory activity was tested by T-test. Our analysis has confirmed that 100&micro;g of plant extract showed high amount of antioxidant activity (78%). The cytokine inhibitory percentage of our plant extract showed consistent increase when tested from 250 ug/ml to 1000ug/ml to be from 24% to 39% thus demonstrating significantly high level of anti-inflammatory potential (P &gt; 0.01). Our study suggests that LA plant can be safely utilized for testing and developing products based on its extract.
%0 - Journal Article
%I - 
%@ - 0125-895